Jobs

Short Description   The Assistant to Head IT / Team Assistant acts as a central coordination point between IT management, internal teams and internal/external stakeholders. The position ensures transparency, efficiency, and alignment across IT operations and plays a key role in enabling management decisions through structured reporting and operational insight.  Main Responsibilities   Team and Operational Coordination    Coordinate and manage administrative and organizational activities within the IT department. Maintain and structure IT documentation, contact lists, and governance materials. Support IT leadership in planning and preparing internal and external meetings, presentations, workshops, team events and reports.  Management Support    Act as a central coordination point between the IT Management Team, internal stakeholders, and external partners.  Prepare management briefings and support decision-making through structured information and follow-up.  Stakeholder Management    Support IT Mgt Management with meeting coordination, documentation, and action tracking.  Contribute to maintaining strong, transparent relationships with external partners  Operational Improvement    Identify inefficiencies in administrative and operational workflows and propose pragmatic improvements.  Support the introduction of digital tools and automation to enhance process efficiency.  Maintain awareness of costs and process performance, supporting the IT Management in achieving operational excellence.    Governance and Reporting   Prepare documentation and ensure follow-up for IT leadership and governance meetings.  Support the IT Management Team with invoice tracking and budget transparency (no financial ownership).  Maintain confidentiality and professionalism in all communications and data handling. 

Main Responsibilities   Conception, design, engineering and implementation of infrastructure projects in the cloud Implement security controls, such as firewalls, security groups, and network access controls, to protect cloud infrastructure and data Troubleshoot and resolve issues with cloud infrastructure in a timely manner Design and implement disaster recovery plans for cloud infrastructure services Automate infrastructure management using tools like Bicep Further development of existing Azure environments Analysis of new cloud services and sharing of the acquired knowledge Development of technical solution concepts and presentations Monitor and optimize cloud-based infrastructure performance and costs Provide technical guidance and support to other teams Collaborate with cross-functional teams

Short Description   This PhD position is part of the PREPARE project (Programmable Release of Prophylactic Antibacterial & Response Enhancing agents), a collaborative initiative between the Infection Biology and Biomedical Materials Focus Areas at the AO Research Institute Davos and CK CARE (Prof. Pierre Yves Mantel).  The Ph.D. student will carry out the experimental work at the AO Research Institute Davos under the supervision of Dr. Matteo D'Este in cooperation with Dr Fintan Moriarty and Prof. Pierre Yves Mantel. The formal academic affiliation will be with the University of Fribourg with supervision by Prof. Michael Walch, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine at the University of Fribourg. Fracture-related infection (FRI) remains a major clinical challenge despite current prophylactic strategies. Increasing evidence shows that early infection establishment is driven by rapid formation of Staphylococcus aureus microaggregates and transient impairment of neutrophil antibacterial function following trauma. The PREPARE project aims to address this problem by: Defining the earliest events enabling bacterial survival in the surgical field (aggregate formation, fibrin encapsulation, antibiotic tolerance) Identifying small-molecule immunomodulators that enhance neutrophil antibacterial activity Contributing to the development of next-generation responsive biomaterials for localized infection prevention   Main Responsibilities   Develop a hydrogel responsive to degrading enzymes for on demand release: Identify and select a linker sequence susceptible to enzymatic degradation by neutrophil-secreted enzymes with high specificity, synthetic accessibility, and suitability for subsequent conjugation to hyaluronan. Develop and optimize a di-telechelic crosslinker for hyaluronan hydrogel formation and characterize the resulting gels using NMR, FT-IR, and rheology. Demonstrate enzyme-triggered hydrogel degradation in vitro by monitoring changes in gel properties through rheological analysis. Evaluate the release kinetics of model compounds from the hydrogel using UV spectroscopy or HPLC to assess controlled release performance.   Incorporate small molecule immunomodulators into the hydrogel: Establish robust covalent ligation or encapsulation strategies to load selected immunomodulators into the hydrogel while preserving their biological activity. Develop and characterize hyaluronan-bound small molecule immunomodulator systems, including covalent tethering and enzymatic responsive designs, to prevent diffusion-driven release while enabling enzyme-triggered exposure of modulators. Engineer enzymatically-responsive core-shell microparticles with a core rich of immunomodulators and hyaluronan-based shell to achieve controlled, enzyme-triggered release from micron-scale delivery vehicles.   Evaluate functional performance of the loaded hydrogel: This task will be carried out in close collaboration with the infection biology group at ARI.  Assess neutrophil-triggered hydrogel degradation, release kinetics, and material properties, and determine the biological efficacy of the released modulators using in vitro neutrophil assays relevant to early postoperative infection.   Carrying out this project, the successful candidate will: Apply advanced biomaterials synthesis and characterization techniques  Analyse and interpret complex experimental datasets Report the results to colleagues and present at local and international conferences Contribute to interdisciplinary collaboration with infection biology specialist in ARI within the PREPARE project

Main Responsibilities Analytics & Tracking: Own the setup, governance, and continuous improvement of Google Analytics 4 (GA4) and Google Tag Manager (GTM) across our properties. Ensure accurate tracking, data quality, and event taxonomy so that stakeholders can rely on our reporting. Collaborate with developers and marketers to implement and QA new tags, events, and conversions.   Performance Reporting & Dashboards: Build and maintain automated reports and dashboards (Looker Studio, Power BI) that provide clear, actionable insights. Translate complex data into concise narratives and recommendations for marketing and sales, and leadership. Monitor key KPIs (traffic, engagement, conversions, ROI, ROAS) and proactively highlight risks, and opportunities.   Paid Media Analytics & Audience Management:  Partner with paid media specialists to define, build, and maintain key audiences for acquisition, remarketing, and retention campaigns. Support campaign measurement, attribution, and testing to optimize performance and budget allocation.   SEO & Organic Performance: Conduct keyword gap and performance analyses using analytics and SEO tools. Use data and business intelligence to inform on-site and off-site SEO strategy, content priorities, and technical improvements. Provide regular reporting on organic search performance and recommendations to improve visibility and conversions.   CRM & Salesforce Reporting Support:  Support the team with Salesforce reports and dashboards to connect marketing activity to pipeline and revenue outcomes.   Data Quality, Compliance & Best Practices Champion data quality, consistency, and documentation across marketing analytics. Support adherence to privacy, consent, and tracking regulations in collaboration with legal/IT as needed.