Jobs

Short Description   We are seeking a proactive and customer-focused IT Supporter to provide technical assistance and support to the AO employees. The successful candidate will be responsible for troubleshooting hardware and software issues, supporting end users, maintaining IT equipment, and ensuring the smooth operation of IT systems and services. Since the role is officialy based in the AO headquarters, a proximity living in Davos area is strongly desired. Main Responsibilities   Ensure first-level support for users via phone, email, and on-site for software and hardware issues. Install and set up hardware for end-users. Document and track all support requests in our ticketing system. Maintain and update user documentation and the knowledge base. Provide support for internal training courses and events. Collaborate on internal IT projects as needed. Support our offices in Davos, Zizers and Zurich.

Employment type / Anstellungsverhältnis:  Permanent Workload percentage / Pensum:  100% Location / Standort:   Davos Platz, CH Experience level / gewünschtes Erfahrungsniveau:  Experienced professional Application language / Bewerbungssprache:  English or German Short Description   As Project Manager - Medical Simulation, you will bridge the gap between practical execution and strategic vision, ensuring our simulation-based education programs maintain the highest standards while evolving to meet future needs. You will be instrumental in bringing cutting-edge simulation technologies to healthcare professionals around the world. Main Responsibilities   Operational Management Execute the setup, operation, and maintenance of simulation equipment for international training events Manage biological specimen handling and logistics in compliance with international regulations Coordinate logistical aspects of simulation-based training events in Davos and support global locations Oversee import/export requirements for specialized training materials Maintain and organize simulation equipment, tools, and supplies inventory   Project Implementation Implement simulation-based training projects from planning to delivery Track project milestones, timelines, and deliverables Resolve operational challenges during project execution Document processes and outcomes to support continuous improvement Coordinate cross-functional team activities to achieve project goals   Technology & Innovation Support the evaluation of novel, simulation-based learning experiences  Contribute to the development and go2market of digital simulation tools Assist in managing relationships with technology and service partners Provide input on scalability opportunities for simulation programs Help implement emerging technologies in simulation education

Employment type / Anstellungsverhältnis:  Temporary Workload percentage / Pensum:  100% Location / Standort:   Davos Platz, CH Experience level / gewünschtes Erfahrungsniveau:  Students / Interns Application language / Bewerbungssprache:  English or German Short Description   Fracture-related infection (FRI) remains one of the most challenging complications in orthopaedic trauma, frequently resulting in bone destruction, implant failure, and prolonged treatment. Recent evidence suggests that early infection-induced bone loss is primarily driven by neutrophil-mediated inflammation and proteolytic degradation, alongside classical osteoclast-driven pathways.  This project (DONUT – Development of advanced Osteolysis Model drive by NeUTrophils) aims to further our knowledge on this topic by developing a novel human-relevant 3D in vitro model that integrates: Spatially organized bone constructs generated using Sound-Induced Morphogenesis Integration of immune cell populations including neutrophils Controlled introduction of Staphylococcus aureus Advanced molecular and imaging-based readouts The project will enable mechanistic insights into infection-induced osteolysis and provide a platform for testing new therapeutic strategies.   Start of work: Position will remain open until role is filled, preferred start by October 2026. Duration: 4 years Main Responsibilities   Develop and optimise 3D biofabricated bone model with immune cells Establish infection models with Staphylococcus aureus Introduce and study neutrophil-driven inflammatory processes Apply advanced analytical techniques (e.g. imaging, transcriptomics, cytokine profiling) Analyse and interpret experimental data Contribute to scientific publications and presentations

Employment type / Anstellungsverhältnis:  Temporary Workload percentage / Pensum:  100% Location / Standort:   Davos Platz, CH Experience level / gewünschtes Erfahrungsniveau:  Students / Interns Application language / Bewerbungssprache:  English or German Short Description This PhD position is part of the PREPARE project (Programmable Release of Prophylactic Antibacterial & Response Enhancing agents), a collaborative initiative between the Infection Biology and Biomedical Materials Focus Areas at the AO Research Institute Davos and CK CARE (Prof. Pierre Yves Mantel).  The Ph.D. student will be formally affiliated with the University of Fribourg and will be co-supervised by Prof. Michael Walch, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine at the University of Fribourg. Fracture-related infection (FRI) remains a major clinical challenge despite current prophylactic strategies. Increasing evidence shows that early infection establishment is driven by rapid formation of Staphylococcus aureus microaggregates and transient impairment of neutrophil antibacterial function following trauma. The PREPARE project aims to address this problem by: Defining the earliest events enabling bacterial survival in the surgical field (aggregate formation, fibrin encapsulation, antibiotic tolerance) Identifying small-molecule immunomodulators that enhance neutrophil antibacterial activity Contributing to the development of next-generation responsive biomaterials for localized infection prevention    Start of work: Position will remain open until role is filled, preferred start by October 2026.  Duration: 4 years  Main Responsibilities   Establish and optimise advanced 3D in vitro infection models (e.g. staphylococcal abscess communities) Investigate early events in infection establishment, including bacterial aggregation, fibrin encapsulation, and antibiotic tolerance Characterise neutrophil–bacteria interactions, including phagocytosis, ROS production, and bacterial killing Identify and evaluate immunomodulatory compounds that enhance neutrophil function Perform cell culture and co-culture experiments using primary human neutrophils and bacterial pathogens Apply advanced techniques including confocal microscopy, flow cytometry, and molecular assays Analyse and interpret complex experimental datasets Contribute to interdisciplinary collaboration with biomaterials researchers within the PREPARE project